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Diabetes - Chronic Complications Chronic complications are perhaps the most feared, even though when they are caught early there is a chance of reversing some of the processes. It is only when there is an end, stage process working (that is, when there has been cell damage or destruction) that little can be done. Possible Complications of Diabetes Any Time The Body Chemistry is out of balance, there are bound to be adverse changes in body tissue. The environment, the things you eat, the stresses you are under, and whatever illnesses or disabilities you may be fighting all make a difference in the physiology of your body (that is, the way your body responds). Diabetes - There are Five Different Types of Neuropathy Distal Symmetrical Polyneuropathy This type, also called simply polyneuropathy, involves the feet and legs and is usually described by the person as numbness or tingling in the feet. Sometimes a burning sensation is noted. Normalizing blood-glucose levels is the best treatment at present.